Comparing any two colors
Color Compare takes each color from wherever it comes from: a screen color, Lab values, CMYK printed through any of huebic's printing profiles, a PANTONE code, or a name from a library you kept in the CxF Viewer. Both are turned into Lab (D50, 2°), the way print is measured, and compared there.
Below the ΔE numbers, the difference is split into its parts: ΔL* lighter or darker, ΔC* more or less colorful, ΔH* a shift in hue. That tells you what to correct, not just how much. CMC 2:1 is the formula textiles and packaging often use.
Try the same CMYK through two profiles with A → B: for example FOGRA39 (measured M0) against PSO Coated v3 / FOGRA51 (measured M1). The ΔE shows how much the same ink numbers drift when the printing standard changes.